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Cannot extract mailbox messages from the Exchange backup error

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I need a solution

I am running an Exchange 2010 on Server 2008 R2 and trying to backup my Exchange databases with GRT with Backup Exec 2012 with all of the updates installed. Some of the backups will go through just fine. Then others will give me this error: 

Final error: 0xe0000393 - Cannot extract mailbox messages from the Exchange backup. Review the job log for more information.

Then when I look in the logs I find this: Backup- \\ADVORLEXCH01.INTERNAL.ADVREF.COM\Microsoft Information Store\General Mailboxes

V-79-57344-915 - Unable to complete the operation.  The following error was returned when opening the Exchange Database file:  '-1022 There is a disk IO error. '

 

Backup- \\ADVORLEXCH01.INTERNAL.ADVREF.COM\Microsoft Information Store\Administrative Mailboxes
V-79-57344-915 - Unable to complete the operation. The following error was returned when opening the Exchange Database file: '-1022 There is a disk IO error. ' 

This was supported to be fixed in Backup Exec 2010 so why am I getting this from time to time in 2012?

And this is just one of the issues I am having with the Exchange backup.


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