Migrating the SQL Express DB to another SQL DB instance ?

People,

At the moment my Backup Exec 15 database is running on 

Microsoft SQL Server 2008 R2 Express Edition (32 bit) (SP2) - 10.50.4000.0 

which I'd like to migrate it into Microsoft SQL Server 2012 Standard Edition (64-bit) (SP2) - 11.0.5343.0 

so how to do that safely without leaving any issue to the current backup job & SQL DB maintenance task if there is any ?

Thanks